Microwave Frequency Electromagnetic Fields (EMFs) Produce Widespread Neuropsychiatric Effects Including Depression

Introduction

Non-thermal microwave and lower frequency electromagnetic fields (EMFs) influence the nervous system through the activation of voltage-gated calcium channels (VGCCs). This review explores whether low-intensity microwave EMFs produce consistent neuropsychiatric effects, known as microwave syndrome, and examines the mechanisms behind these effects.

Mechanism of Action

VGCCs are prevalent throughout the nervous system, playing crucial roles in the release of neurotransmitters and neuroendocrine hormones. Evidence shows that calcium channel blockers can inhibit the effects of EMFs, supporting the role of VGCCs in mediating these impacts.

Evidence from Literature

Both Soviet and Western studies indicate that non-thermal microwave exposures affect the brain and peripheral nervous system, leading to significant changes in nervous system histology and function. This is thought to be due to VGCC activation, resulting in excessive release of neurotransmitters and neuroendocrine hormones, as well as oxidative and nitrosative stress.

Genetic and Epidemiological Studies

Genetic polymorphism studies suggest that excessive VGCC activity can cause neuropsychiatric changes in humans. Historical U.S. government reports from the 1970s and 1980s, based on occupational exposure studies, provide evidence of various neuropsychiatric effects due to non-thermal microwave EMFs.

Recent Epidemiological Studies

Eighteen contemporary epidemiological studies reinforce the evidence that microwave EMFs from cell phone base stations, excessive cell phone use, and wireless smart meters are linked to similar neuropsychiatric effects. Several studies demonstrate clear dose-response relationships. Additional studies hint that short wave, radio station, occupational, and digital TV antenna exposures might cause comparable neuropsychiatric effects.

Reported Neuropsychiatric Changes

Commonly reported neuropsychiatric changes include:

• Sleep disturbances/insomnia
• Headaches
• Depression and depressive symptoms
• Fatigue and tiredness
• Dysesthesia (abnormal sensation)
• Concentration and attention dysfunction
• Memory changes
• Dizziness
• Irritability
• Loss of appetite and body weight
• Restlessness and anxiety
• Nausea
• Skin burning/tingling/dermographism
• EEG changes

Conclusion

The mechanisms involving VGCCs, the non-thermal effects of EMFs on the brain, and extensive epidemiological studies over the past 50 years collectively demonstrate that various non-thermal microwave EMF exposures produce a wide range of neuropsychiatric effects. These findings are supported by five criteria testing for causality, solidifying the link between EMF exposure and neuropsychiatric health issues.